| >> إسم الكتاب : | Swine-Flu -INFLUENZA |
| >> إسم المؤلف : | BY QHSE DEPT |
| >> حجم الكتاب : | - - - |
| >> نوع الكتاب : | أكروبات |
| >> تحميل الكتاب : | إضغط هنا للتحميل |
| >> زيارات الكتاب : | 602 |
| >> تاريخ الإضافة : | الأحد 24/05/2009 11:44:34 مساء |
Monday, December 28, 2009
Swine-Flu -INFLUENZA
Medical Laboratory Techniques and Quality Control
| >> إسم الكتاب : | Medical Laboratory Techniques and Quality Control |
| >> إسم المؤلف : | Dr.Janet A. Misak |
| >> حجم الكتاب : | - - - |
| >> نوع الكتاب : | وورد |
| >> تحميل الكتاب : | إضغط هنا للتحميل |
| >> زيارات الكتاب : | 305 |
| >> تاريخ الإضافة : | الأحد 22/11/2009 06:10:43 صباحاً |
Wednesday, November 25, 2009
Continuing controversy about the drug «interferon» Egyptian
Congress has not been without the participation of dozens of senior doctors and professors of the liver in Egypt and the Arab world, who discussed the matter of Egypt and the growth rates of liver disease in Egypt, and the recent controversy about the decision of the health insurance using the product for the treatment of HIV EGYPTIAN «C», and many discussions around the between cast doubt on the effectiveness, and make a reservation to a consensus on the results.
«Egyptian today» spotted discussions Egyptian and foreign specialists on the effectiveness of the drug, and explored the views of the various parties.
Discussions about the medication for the treatment of HBV «C» on the decision of the Health Insurance Authority to provide a drug for the treatment of patients EGYPTIAN virus «C», and effectiveness, and as confirmed by the doctors and professors liver efficacy of Egypt and some of them said they had received in their clinic patients who underwent treatment for his for a year and then came a setback, others pointed out that the drug is needed between two and more to get the final results and statistical evidence of its effectiveness. And another group confirmed that at least in any way for Almthail foreign.
Dr. AH El-Taher, a professor of internal medicine and gastroenterology and hepatology at the Qasr Al-Aini School of Medicine, reviewed the experience with the drug for the treatment of HIV Egyptian «C», saying: «I have tried it already, I would say that effective in the continuous treatment, and refers to no response, but the problem remains that the high relapse rates among users, ie, after the end of the treatment by the bounce of the disease by up to 40%, note that the problem of relapse is not limited to the Egyptian pharmaceutical and talked with all Alinterveronat ranging between 50 and 60% according to studies of global foreign branded generics «Magazine Global liver in 2009 »and therefore the success rate of treatment in the neighborhood of 50% is considered a reasonable rate was the treatment Balintervin and ribavirin together according to the latest scientific studies of local and global, these words on the lips of a. d. Gamal Esmat.
HIV treatments «C» in Egypt were the focus of the meeting, which collected both by Dr. Jamal Shiha, a professor in the liver, Mansoura University, chairman of care for patients with liver, Oxim Coutts, President of the German Society for the Protection of hepatitis, the representative of Europe in the Global Alliance for Hepatitis A, where Shiha reviewed the drugs used in the treatment of patients with HIV «C» in Egypt, referring to the controversy raised recently on the contract of the General Authority for health insurance with an Egyptian company in the private sector «Ryan Mena Farm», for the supply of drug Reifeanor Retarder, to treat patients with HIV «C» from the insured them, and the effectiveness of the drug or not.
«Shiha,» he told «COUTTS»: «We are happy when we hear the production of Egyptian medicine, medicine or the existence of less expensive drugs produced by international companies, but should be effective medicines, since it concerns the health of citizens», citing a study prepared Institute in Mansoura, liver, and the other at the University of Ain Shams, and added that the General Authority for health insurance based its decision to supply the drug in one study only confirm the existence of a positive outcome to him, pointing out that the study «doubtful» as he put it, and that the preferred drug for low price and that it is registered in the Ministry of Health.
Study, which concerned d. Jamal Shiha is a study by two senior specialists in the treatment of liver diseases, namely Prof. Dr. Gamal Esmat - which was regarded as a pioneer in the clinical trials of interferon in Egypt and the world, the President of the World Federation of the liver - in partnership with the world, Dr. Sheriff Abdel-Fattah .. The study was published in the magazine world was the result that the success rate of treatment with Egyptian medicine, a between 50% -55% are located in the same limits published for foreign drugs for the strain of the virus in Egypt, the kind of gene 4.
The finding was consistent with the views of some senior professors in the field of liver and with Prof. Dr. SE Qasr Al-Aini Zakaria professor who described the famous Egyptian medicine as a rival good, as well as the safety of Professor Dr. Mohsen liver liver Menoufia Institute, who confirmed that Egyptian medicine not only as effective but the effectiveness of foreign and price together a great addition to the patient of Egypt.
Dr. Ashraf Omar, a professor at Cairo University Liver, secretary of the Egyptian Society for liver cancer, seen from the side that the Ministry of Health is responsible for evaluation of treatment, and are either allowed it negotiable that would mean that it is safe and useful in the interest of the patient, or that in some cases, they are register medicines approved by the Agency U.S. Food and Drug «FDA» with the passage of time as proven ineffectual or can not be proven, although registered in the United States, for example, pointing out that he himself was on his way to get the final results determine the effectiveness of the drug «Raeveron Retarder», which takes time at least two or three years, to be tested in a large sample of patients can develop statistics and indicators on them, determine the extent of response and side effects to be used, he said. Required to intensify awareness campaigns, viral hepatitis, and methods of prevention, owing to the contribution of these campaigns is to reduce the risk of the disease.
In Cairo, met with the «Egyptian today» Dr. Wafik Bardisi, Chairman of the Board of Directors «Mena Farm» to answer questions raised on the sidelines of the 60 annual conference of the American Association for the Study of Liver Diseases, and explained that the company contracted in 1997 with «Ryan Bayutk» German - a is not a drug company - is one of the leading companies in research and genetic engineering, has been contracted to a joint research project, which cost millions of pounds - he said - the contract was signed and documented at the Egyptian Embassy in Germany, the Ministry of Health in Egypt in preparation for the production of «interferon Egyptian-German ».
He Bardisi: «Because the cost was very high on our (Ryan Bayutk) to pay part and enter the German side a partner with us .. Company was established (Ryan Mena Farm), and conducted the production process and development over the past two and a half year, in cooperation with the research group from the Netherlands, reached the product is consistent and stable laboratory, not a copycat of interferon, produced by the two companies Roche and Schering Wars,
On the steps of registering the drug, he said Bardisi: «our progress medicine registration papers, and presented to the 7 committees, and asked for amendments, sent to a German company have been implemented, and an additional clinical trials and the results came out very promising .. Been registered medicine in Egypt under the name of national Kmsthoudr EGYPTIAN nothing to do with Germany only in terms of technical,
As human knowledge and registration are limited to Mena Farm, was not the prosecution at any stage that the product is registered in Germany, as this would require a document stating so for the Ministry of Health in Egypt, and therefore raise the issue of the drug is registered or not registered in Germany and the purpose of sanctions with the erosion the success of the product which was hailed by human rights groups, including the Association in America and described the Egyptian model of cooperation with the country for providing advanced high-tech medicines and appropriate prices for the poor as a model should be followed by all developing countries »,
He added: «We now arises in connection with the effectiveness of the product and published in scientific journals after his success in the global market coincides with the decision of the Ministry of Health and its inclusion in health insurance is not a coincidence, but certainly the result of arson and contrary to the decision with interest».
He continued: decision was issued by the Pricing Committee of the Ministry of Health exemption from taxes, and that the pharmacist takes only 10% profit from the sale of medicine because it is vital, although the law stipulates that the pharmacist gets 20% from the sale of drugs manufactured locally, and established a factory for the production of medicine in collaboration between experts from Germany and Egyptians .. It is the first and later in Egypt and the Middle East and Africa.
The Bardisi that many of the scientific and clinical studies underway in Egypt, Europe and the results promising and uncertain, also published refereed journal, with the increase in consumption is observed, which emphasizes the medical community welcomed the medicine will be reflected on the cost of production will not hesitate to reduce the price below a minimum .. We are the decision makers here in Cairo for the company and the citizens together .. Not in favor of the company only.
Dr Anwar al-Nasr, scientific director of the office of the company, that the property is in the market since more than 3 years, and at 370 pounds, and was conducted by multidisciplinary research began with 50 patients in the Qasr Al-Aini, and reached to 100 and now in 1300 under the patient, and added: «There 200, a liver specialist and professor of medicine in their clinics writing to date, and is installed in Alruchtat,
The Ministry of Health contracted with the company, following a decision of the National Committee on viral hepatitis, consisting of doctors in the liver are the lords of Egypt, because the drug tests conducted by him and published abroad, began to be used in Ahmed Maher Teaching Hospital, in addition to all university hospitals and government bodies and private hospitals, which use it for years after that documented in its effectiveness.
He continued: «With the increase in consumption has been a meeting between officials of the company, Dr. Said salary, the President of the Health Insurance Authority, which offered lower the price of medicine for the body for up to 225 pounds, note that the price of the product in which about a quarter of the importer has contributed to the efforts of the Ministry of Health to put pressure on international companies interferon to reduce the price of 1400 pounds for injection to 480 pounds, and for us to imagine the size of exploitation and profits made by these companies over the years, companies did not find what you're saying because of the effectiveness of the drug from the analytical point of at least .. He was able to use their own laboratories in the analysis of large dosage, but did not prove anything ».
And he added. Insist that the results of the drug ranging between 45 and 60% so far .. and will soon announce the results in more detail .. As the drug by several research published in leading international journals «magazine digestive diseases - liver - 2009» ..
As one of the greatest scholars of his class interferon Professor Anthony Meagher of the three long-acting formulations only in the world, in addition to 30 research professors from Egyptian universities in Cairo and Ain Shams, Al-Azhar, Alexandria, Tanta and Assiut and the Institute of the liver, stressing the effectiveness of the product and its limited side effects, especially affecting the properties of blood, In addition to research and other studies published in the magazine «blood», and «Research interferon» World Wars.
For his part, Dr. Gamal Esmat, a professor of liver diseases at Cairo University, a member of the National Committee on viral hepatitis, the presence of drug «Raeveron Retarder» Egyptian causing pressure on foreign companies producing interferon, prompting them to reduce the price, and put up CD Alrebaviren free of charge, and assisted companies in awareness campaigns about the disease, I believe that the reluctance of some foreign companies to enter medicine in the war against the Egyptian pharmaceutical industry.
He pointed out that other studies confirmed the efficacy of Egypt, including a study conducted at the National Institute of the liver. She explained that the effectiveness of quite convergent with other drugs, except for cases of excessive fibrosis.
According to Dr. Hatem Esmat the mountain, and the current health minister, and its knowledge of the cause of hepatitis in Egypt, and received a discount of two companies that produce the drug to the package price of less than 1500 to 400 pounds and the existence of the property to pay the Egyptian foreign companies to reduce prices.
استمرار الجدل حول عقار «الإنترفيرون» المصرى
كتب محمد طلعت الهوارى ٢٥/ ١١/ ٢٠٠٩
مناقشات علمية، توصيات، تجارب، وأكثر من ٢٠٠٠ بحث، و٧٠٠٠ مشارك، ساهمت معاً فى تشكيل فعاليات مؤتمر الجمعية الأمريكية لدراسات أمراض الكبد هذا العام، والذى عُقد فى مدينة بوسطن الأمريكية فى الفترة بين ٣١ أكتوبر و٣ نوفمبر.
ولم يخل المؤتمر من مشاركة العشرات من كبار أطباء وأساتذة الكبد فى مصر والعالم العربى، والذين ناقشوا الشأن المصرى ومدى نمو معدلات الإصابة بأمراض الكبد فى مصر، والجدل الدائر مؤخراً حول قرار هيئة التأمين الصحى باستخدام مستحضر مصرى لعلاج فيروس «سى»، وتعددت المناقشات حوله ما بين تشكيك فى فاعليته، وتحفظ على إبداء الآراء حول نتائجه.
«المصرى اليوم» رصدت مناقشات المتخصصين المصريين والأجانب حول فاعلية العقار، واستطلعت آراء الأطراف المختلفة.
المناقشات حول الأدوية المخصصة لعلاج فيروس الالتهاب الكبدى «سى» تناولت قرار هيئة التأمين الصحى تقديم عقار مصرى لعلاج مرضى فيروس «سى»، ومدى فاعليته، وفى الوقت الذى أكد فيه أطباء وأساتذة كبد فاعلية العقار المصرى وذكر بعضهم أنهم استقبلوا فى عياداتهم مرضى خضعوا للعلاج له لمدة عام ثم تعرضوا لانتكاسة، أشار آخرون إلى أن العقار يحتاج ما بين سنتين وأكثر للحصول على النتائج النهائية والدلائل الإحصائية لمدى فاعليته. ومجموعة أخرى أكدت أنه لا يقل بأى حال من الأحوال عن المثائل الأجنبية.
الدكتور طاهر حسن الزناتى، أستاذ الأمراض الباطنية والجهاز الهضمى والكبد فى كلية طب قصر العينى، استعرض تجربته مع العقار المصرى لعلاج فيروس «سى» قائلاً: «لقد جربته بالفعل، ويمكننى القول بأنه فعال فى العلاج المستمر، ويشير إلى وجود استجابة، ولكن تبقى المشكلة فى أن معدلات الانتكاسة عالية بين مستخدميه، أى أنه بعد انتهاء فترة العلاج به يرتد المرض بنسبة تصل إلى ٤٠%، علماً بأن مشكلة الانتكاسة غير مقصورة على الدواء المصرى وتحدث مع جميع الإنترفيرونات وتتراوح بين ٥٠ و٦٠٪ وفقاً للدراسات العالمية على الأدوية المثيلة الأجنبية «مجلة الكبد العالمية لعام ٢٠٠٩» وبالتالى فإن نسبة نجاح العلاج فى حدود ٥٠٪ تعتبر هى النسبة المعقولة للعلاج بالإنترفين والريبافيرين معا حسب آخر الدراسات العلمية المحلية والعالمية وهذا الكلام على لسان أ.د. جمال عصمت.
علاجات فيروس «سى» فى مصر كانت محور اللقاء الذى جمع كلاً من الدكتور جمال شيحة، أستاذ الكبد فى جامعة المنصورة، رئيس جمعية رعاية مرضى الكبد، وأكسيم كاوتس، رئيس الجمعية الألمانية للحماية من الالتهاب الكبدى، ممثل أوروبا فى التحالف العالمى للالتهاب الكبدى، حيث استعرض شيحة الأدوية المستخدمة فى علاج مرضى فيروس «سى» فى مصر، وأشار إلى الجدل الذى أُثير مؤخراً حول تعاقد الهيئة العامة للتأمين الصحى مع شركة مصرية بالقطاع الخاص «راين مينا فارم»، لتوريد عقار رايفينور ريتارد، لعلاج مرضى فيروس «سى» من المؤمن عليهم، ومدى فاعلية العقار من عدمه.
«شيحة» قال لـ«كاوتس»: «إننا نسعد عندما نسمع بإنتاج دواء مصرى، أو بوجود دواء أقل فى السعر من الأدوية التى تنتجها الشركات العالمية، لكن يجب أن تكون أدوية فعالة لأن الأمر يتعلق بصحة المواطنين»، مستنداً فى ذلك إلى دراسة أُعدت فى معهد الكبد فى المنصورة، وأخرى فى جامعة عين شمس، وأضاف أن الهيئة العامة للتأمين الصحى استندت فى قرارها بتوريد العقار على دراسة واحدة فقط تؤكد وجود نتائج إيجابية له، مشيراً إلى أن الدراسة «مشكوك فيها» على حد تعبيره، وأن الهيئة فضلت العقار لانخفاض سعره ولأنه مسجل فى وزارة الصحة.
الدراسة التى يعنيها د. جمال شيحة هى دراسة قام بها اثنان من كبار المتخصصين فى علاج أمراض الكبد وهما الأستاذ الدكتور جمال عصمت- وهو الذى يعتبر رائداً فى التجارب الإكلينيكية للإنترفيرون فى مصر والعالم ورئيس الاتحاد العالمى للكبد- بالاشتراك مع العالم الأستاذ الدكتور شريف عبدالفتاح.. ونشرت الدراسة فى مجلة عالمية وكان نتيجتها أن نسبة نجاح العلاج بالدواء المصرى وهى ما بين ٥٠٪-٥٥٪ تقع فى نفس الحدود المنشورة للأدوية الأجنبية بالنسبة لنوع الفيروس المنتشر فى مصر وهو من النوع الجينى ٤.
وتأتى هذه النتائج متماشية مع آراء بعض الأساتذة الكبار فى مجال الكبد ومعهم الأستاذ الدكتور سراج زكريا أستاذ قصر العينى المشهور الذى وصف الدواء المصرى بأنه منافس جيد، وكذلك الدكتور محسن سلامة أستاذ الكبد بمعهد الكبد بالمنوفية الذى أكد أن الدواء المصرى ليس فقط بنفس فاعلية الأجنبى لكن فاعليته وسعره معا إضافة عظيمة للمريض المصرى.
الدكتور أشرف عمر، أستاذ الكبد فى جامعة القاهرة، سكرتير الجمعية المصرية لسرطان الكبد، يرى من جانبه أن وزارة الصحة مسؤولة عن تقييم العلاج، وأنها إما سمحت بتداوله فذلك يعنى أنه آمن ومفيد لمصلحة المريض، أو أنه فى بعض الأحيان يتم تسجيل أدوية معتمدة من الوكالة الأمريكية للغذاء والدواء «FDA» مع مرور الوقت حيث يثبت عدم فاعليتها أو لا يثبت، على الرغم من تسجيلها فى الولايات المتحدة الأمريكية على سبيل المثال، مشيراً إلى أنه شخصياً فى طريقه للحصول على نتائج نهائية تحدد مدى فاعلية عقار «رايفيرون ريتارد»، وهو ما يحتاج إلى وقت لا يقل عن سنتين أو ثلاث، على أن يتم تجريبه على عينة كبيرة من المرضى يمكن وضع إحصائيات ومؤشرات بناءً عليها، تحدد مدى الاستجابة والأعراض الجانبية لاستخدامه، على حد قوله. مطالباً بتكثيف حملات التوعية بالفيروسات الكبدية وطرق الوقاية منها، نظراً لمساهمة هذه الحملات فى تقليل مخاطر الإصابة بالمرض.
وفى القاهرة التقت «المصرى اليوم» الدكتور وفيق البرديسى، رئيس مجلس إدارة شركة «مينا فارم» للإجابة عن التساؤلات التى طُرحت على هامش المؤتمر السنوى الـ٦٠ للجمعية الأمريكية لدراسات أمراض الكبد، وأوضح أن الشركة تعاقدت عام ١٩٩٧ مع شركة «راين بايوتك» الألمانية- وهى ليست شركة أدوية- إنما إحدى الشركات الرائدة فى مجال الأبحاث والهندسة الوراثية، وتم التعاقد على مشروع بحثى مشترك، وهو ما تكلف ملايين الجنيهات- على حد قوله- وتم توقيع العقد وتوثيقه فى السفارة المصرية بألمانيا، وفى وزارة الصحة بمصر تمهيداً لإنتاج «الإنترفيرون المصرى الألمانى».
وتابع البرديسى: «نظراً لأن التكلفة كانت عالية للغاية عرضنا على (راين بايوتك) أن ندفع جزءاً ويدخل الجانب الألمانى شريكاً معنا.. وتم تأسيس شركة (راين مينا فارم)، وأُجريت عملية الإنتاج والتطوير على مدار سنتين ونصف السنة، بالتعاون مع مجموعة بحثية من هولندا، توصلت إلى منتج ثابت ومستقر معملياً، ليس تقليداً أعمى للإنترفيرون الذى تنتجه شركتا روش وشيرينج العالميتان،
وحول خطوات تسجيل الدواء، قال البرديسى: «تقدمنا بأوراق تسجيل الدواء، وعُرضت على ٧ لجان، وطلبوا تعديلات أرسلناها إلى الشركة الألمانية وتم تنفيذها، كما أجرينا تجارب إكلينيكية وخرجت نتائج مبشرة جداً.. وتم تسجيل الدواء فى مصر تحت اسم شركة وطنية كمستحضر مصرى لا علاقة له بألمانيا إلا من حيث التقنية،
أما حقوق المعرفة والتسجيل فهى مقصورة على شركة مينا فارم، ولم يتم الادعاء فى أى مرحلة بأن المستحضر مسجل فى ألمانيا، حيث إن ذلك يتطلب وثائق تفيد بذلك تقدم لوزارة الصحة المصرية، ولذلك فإن إثارة موضوع أن الدواء مسجل أو غير مسجل فى ألمانيا غرضها الشوشرة والانتقاص من نجاح المستحضر الذى أشادت به جمعيات حقوق الإنسان، ومنها جمعية فى أمريكا وصفت هذا النموذج المصرى للتعاون مع بلاد متقدمة لتوفير أدوية ذات تقنية عالية وأسعار مناسبة للفقراء بأنه نموذج يجب أن تحتذيه جميع البلاد النامية»،
وأضاف: «وما يثار الآن بصدد فاعلية المستحضر وما نشر فى المجلات العلمية العالمية بعد نجاحه فى السوق يتزامن مع قرار وزارة الصحة بإدراجه فى التأمين الصحى ليس بمحض الصدفة ولكنه بالتأكيد بفعل فاعل ويتعارض القرار مع مصلحته».
وتابع: صدر قرار بواسطة لجنة التسعير التابعة لوزارة الصحة بإعفائه من الضرائب، وبأن يأخذ الصيدلى ربحاً ١٠% فقط من بيع الدواء لأنه حيوى، على الرغم من أن القانون ينص على أن الصيدلى يحصل على نسبة ٢٠% من بيع الأدوية المصنعة محلياً، كما أسسنا مصنعاً لإنتاج الدواء بالتعاون بين خبراء ألمان ومصريين.. ويعتبر الأول والأحدث فى مصر والشرق الأوسط وأفريقيا.
وأكد البرديسى أن العديد من الدراسات العلمية والإكلينيكية جارية فى مصر وأوروبا ونتائجها مبشرة ومؤكدة، كما نشرت مجلات علمية متخصصة، ومع زيادة الاستهلاك الملحوظ حالياً الذى يؤكد ترحيب المجتمع الطبى بالدواء سينعكس ذلك على تكلفة الإنتاج ولن نتردد فى أن نخفض السعر دون حد أدنى.. فنحن أصحاب القرار هنا فى القاهرة لصالح الشركة والمواطن معا.. وليس لصالح الشركة فقط.
وأشار الدكتور أنور نصر، مدير المكتب العلمى بالشركة، إلى أن العقار موجود فى الأسواق منذ أكثر من ٣ سنوات، وبسعر ٣٧٠ جنيهاً، وأجريت عليه أبحاث متعددة بدأت بـ٥٠ مريضاً فى قصر العينى ثم وصلت إلى ١٠٠ والآن فى إطار ١٣٠٠ مريض، وأضاف: «هناك ٢٠٠ طبيب وأستاذ كبد متخصص يكتبون الدواء فى عياداتهم حتى تاريخه، كما هو مثبت فى الروشتات،
كما تعاقدت وزارة الصحة مع الشركة، بعد قرار من اللجنة القومية لمكافحة الفيروسات الكبدية، المكونة من أطباء هم أباطرة الكبد فى مصر، لأن العقار أجريت عليه تجارب ونُشر عنه فى الخارج، وبدأ استخدامه فى مستشفى أحمد ماهر التعليمى، إضافة إلى جميع المستشفيات الجامعية والهيئات الحكومية والمستشفيات الخاصة التى تستعمله منذ سنين بعد أن وثقت فى فاعليته.
وتابع: «ومع زيادة الاستهلاك تم لقاء بين مسؤولى الشركة، والدكتور سعيد راتب، رئيس هيئة التأمين الصحى، عرضنا خلاله تخفيض سعر الدواء للهيئة ليصل إلى ٢٢٥ جنيهاً، علماً بأن السعر للمستحضر الذى يوازى ربع المستورد قد ساهمت فيه مجهودات وزارة الصحة للضغط على الشركات العالمية لتخفيض سعر الإنترفيرون من ١٤٠٠ جنيه للحقنة إلى ٤٨٠ جنيهاً، ولنا أن نتصور حجم الاستغلال والأرباح التى حققتها هذه الشركات على مدار سنوات، ولم تجد الشركات العالمية ما تقوله نظراً لفاعلية الدواء من الناحية التحليلية على الأقل.. وكان بإمكانهم استخدام معاملهم الضخمة فى تحليل الدواء ولكنهم لم يثبتوا شيئاًً».
وأوضح د. نصر أن نتائج العقار تتراوح بين ٤٥ و٦٠% حتى الآن..وستُعلن قريباً النتائج بشكل أكثر تفصيلاً.. كما أن العقار نشر عنه عدة أبحاث فى كبرى المجلات العالمية «مجلة أمراض الهضم- الكبد- ٢٠٠٩»..
كما صنفه أحد أكبر علماء الإنترفيرون البروفيسور أنتونى ميجر من بين ثلاثة مستحضرات طويلة المفعول فقط فى العالم، إضافة إلى أبحاث ٣٠ أستاذاً مصرياً من جامعات القاهرة وعين شمس والأزهر والإسكندرية وطنطا وأسيوط ومعهد الكبد، مؤكدة فاعلية المستحضر والأعراض الجانبية المحدودة، خاصة المؤثرة على خصائص الدم، إضافة إلى أبحاث ودراسات أخرى نُشرت فى مجلتى «الدم»، و«بحوث الإنترفيرون» العالميتين.
من جانبه أكد الدكتور جمال عصمت، أستاذ أمراض الكبد بجامعة القاهرة، عضو اللجنة القومية لمكافحة الفيروسات الكبدية، أن وجود عقار «رايفيرون ريتارد» المصرى تسبب فى الضغط على الشركات الأجنبية المنتجة للإنترفيرون، مما دفعها لتخفيض سعره، وطرح أقراص الريبافايرين مجاناً، وساعدت الشركات فى حملات التوعية حول المرض وفى ظنى أن ما تردده بعض الشركات الأجنبية عن الدواء يدخل فى إطار الحرب ضد صناعة الدواء المصرية.
وأشار إلى أن دراسات أخرى أجريت أكدت فاعلية العقار المصرى، منها دراسة أجريت فى المعهد القومى للكبد. وأوضحت أن فاعليته متقاربة تماماً مع الأدوية الأخرى، ماعدا حالات التليف الزائد.
ووفقاً لعصمت فإن الدكتور حاتم الجبلى، وزير الصحة الحالى، وبحكم معرفته بقضية الالتهاب الكبدى فى مصر، ، وحصل على تخفيض من الشركتين المنتجتين للدواء ليقل سعر العبوة من ١٥٠٠ إلى ٤٠٠ جنيه وأن وجود العقار المصرى دفع الشركات الأجنبية إلى تخفيض أسعارها.
Saturday, November 14, 2009
31 vacancies for pharmacists everywhere [1 Attachment]
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Thursday, October 29, 2009
Friday, October 23, 2009
[PCM] Vacancies everywhere for all pharmacists
Excellency in providing job vacancies If you know someone suitable for this job, forward to him ------------ --------- --------- ------ ![]()
Manager Tips 6 · Assignment; For New; Do That; this Way · Delegation; For Experienced; Do That; ur Way · Empowerment; For Seniors ; Do What u think; ur way
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KSA to KSA N.B. If you "have transferable Iqama", type that in subject field What is Transferable iqama: When you have a residency card in KSA & your sponsor accepts your transferance to onther sponsor(Kafil)
From: "HAMODI" <mohie911@yahoo. com> Vacancy in Abha KSA A fast growing outsourcing team in KSA is searching for a medical rep. with the following criteria : · Transferable IQAMA is a MUST · One year experience in KSA as a medical rep. is a MUST · One Year experience in Abha as a medical rep. is a PLUS (preferred) If u see Yourself complying these demands kindly send your C.V. to : fax: +966 - 02 - 6430166 Sent C.V. should be complying with the above demands
From: "king" <kingseso1@yahoo. com> Multinational pharmaceutical and cosmetic company in Saudi Arabia We are a group of multinational pharmaceutical and cosmetic companies In all regions in Saudi Arabia 1- have a good experience at the same field 2- fluent in both Arabic and English 3- preferred to have transferable Iqama email info@tabmedical. com Fax: 0096626577206 ext 104
From: "job_vacancy321" <job_vacancy321@ yahoo.com> New company for pharmaceutical and cosmotics produsts in ksa - Candidates should be pharmacists. - One year experience in similar position. - Age should be less than 28 years. - Valid Saudi driving license. send your C V with recent photo to the following e-mail address:
From: Amr Bedair <amro.bedair@ gmail.com> Medical Reps for a newly established Pharmaceutical company CVs to be sent before 1/11/2009 on this mail
Egypt to KSA
A multinational Company in the field of Medical Equipment in KSA e-mail: ramisobhy@hotmail. com
TABUK PHARMACEUTICAL MANUFACTURING COMPANYWe are a leading, well-established and fast-growing pharmaceutical company and currently ranked as the 2nd largest local manufacturer in Saudi Arabia. To meet the requirements of our expansion plans, we are seeking highly competent individuals to join us in the following positions: MEDICAL REPRESENTATIVES (Pharmacist only) · At least 2 years of similar experience, preferably with multinational companies · Excellent communication skills · Creativity, Planning & Analytical skills PRODUCT MANAGERS (Pharmacist only) · At least 3 years of similar experience with multinational companies · CNS experience will be an added advantage · Creativity, Planning & Analytical skills · Excellent communication & computer skills We offer excellent working conditions with best in industry incentive scheme and attractive package.Please send your detailed CV with recent photo within one week (maximum) to: P.O. Box 18791 Jeddah 21425 Saudi Arabia Or Fax: 00966 -2-6525647 Or e-mail to: bong@j.tpmc. com.sa Meet Pharmacists_ coffee members on
American International medical group allocated in America, Europe & Latin America will open a new center in Jeddah – KSA The group is offering competitive salaries & excellent working environment. If interested kindly send your resume within 5 days to:
or fax: +973 17582271
Urgently for Saudi Arabia Tel: (+2) 02 33035131 – 33045076 – 0125269999
Egypt to Egypt
Al-Saleheen pharmacy Please contact Dr/Sami A'Moniem Mob: (+2) 0104660964
Pharmacy in Mataria A pharmacist for morning shift Tel: (+2) 02 26529225 - 0105299312
Pharmacies in Bolaq – Faisal – Imbaba Needs pharmacists & assistants Tel: (+2) 02 33822755 – 37430805
Pharmacy in Abbas Al-Akkad Pharmacy located in Abbas Al-Akkad – Nasr City Tel: (+2) 02 24016406 - 22608266
Female pharmacist required For a night shift (from 4:00 – 10:00pm) Tel: (+2) 02 26344377
Male & female pharmacists required Pharmacy located in Manshyet Naser – Autostrad Tel: (+2) 0101131194
Big pharmacy in Mohandeseen Tel: (+2) 02 33351678
Pharmacy in Gesr Al-Suez Pharmacy in Gedr Al-Suez – Gamal A'Naser Tel: (+2) 02 26631150 – 0127944955
Manager pharmacist required Tel: (+2) 0141919764
Pharmacists needed Pharmacies in Badr City & Al-Tagamoa' Al-Khames Male & female pharmacists are needed Tel: (+2) 02 22711382 – 0101726145 – 0105656880
Al-Madina Al-Monawara pharmacy Tel: (+2) 02 25939114 - 0141539155
From: hatem mohammed <hatembasiouni@ yahoo.com>
pharmacy for rent in Alexandaria Pharmacy for rent in Alexandaria Mandara Bahary Behind Hosny Grill Tel: 009660506203934 E-mail hatembasiouni@ yahoo.com
From: "os_abdelmoneim" <os_abdelmoneim@ yahoo.com>
Pharmacy For Rent In Mostafa Al Nahas Street,Nasr City, Cairo. Mob: (+2) 0113334167
From: MOHAMED SHERIF <drmsherifm@yahoo. com>
From: "hmrpharma" <hmrpharma@yahoo. com>
Well established Pharmaceutical company & its Scientific office for Cairo, Giza, Helwan & Sharkia. · graduates of Pharmacy, Veterinary, Science. · Energetic, motivated & self confident.
CVs to be sent to hmrpharma@yahoo. com within one week with title in the subject area.
From: "yhhm2000" <yhhm2000@yahoo. com> AL-ESRAA PHARMACEUTICAL OPTIMA FOR NEW EXPANSION IS SEEKING FOR 1- FULL TIME Med Reps (Ref 01) 2- PART TIME Med Reps (Ref 02) · Candidates must be pharmacist, Vet or Physicians free from military/government obligation · Candidate must be Pharmacist or Physician with 1-2 year experience in the Send your comprehensive resume mentioning the Ref o your Email subject to:
From: mohamed ibrahim <m_ibrahim816@ hotmail.com>
vacancy at sigma Alexandria
Minimum 2-3 years experience in the same position in a reputable pharmaceutical company Kindly mention the job code in the email subject
Leading pharmaceutical company · Medical representatives (all governorates)
ADVOCURE Advocure invites qualified candidates to apply for the following positions: Excellent command of English and MS office
or by Fax: (+2) 02 22576403
ProAct Marketing company A leading pharmaceutical outsourcing Co. Is seeking for its expansion "all governorates": 2- District managers/supervisor s Ref.201 3- Medical reps. [full time] Ref.301 4- Medical reps. [part time] Ref.302 Pharmacists, physicians, vet & science graduates Please send your CV with recent photo to:
------------ --------- --------- --------- --------- --------- --------- --------- ----- If you aren't member Subscribe to pharmacists_ coffee magazine to receive more vacancies To subscribe Send empty e-mail to Pharmacists_ coffee-subscribe@ yahoogroups. com |
Tuesday, October 20, 2009
Young Girl With Clumsiness, Dystonia, and Speech Difficulty
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GSK signs DMD deal with Prosensa

GSK signs DMD deal with Prosensa
GlaxoSmithKline is linking up with Prosensa to develop drugs for Duchenne muscular dystrophy, an agreement that could be worth £428 million to the Dutch biopharmaceutical company.
Under the terms of the deal, GSK has acquired the rights to develop and sell Prosensa’s lead compound, PRO051, an RNA modulating therapeutic which acts by skipping exon 51 of the dystrophin gene. Three other RNA-based compounds, which seek to treat “specific, but different, subpopulations of patients suffering from DMD,” are covered by the agreement.
Cashwise, GSK is making an upfront payment of £16 million and Prosensa is eligible to receive up to £412 million in milestones if all four compounds are successfully developed. The Leiden-headquartere d firm is also entitled to double-digit royalties on product sales and will retain certain commercial participatory rights.
DMD is a severely debilitating neuromuscular disease that affects one in 3,500 newborn boys. Patients suffer from progressive loss of muscle strength due to the absence of the protein dystrophin, often making them wheelchair-bound before the age of 12, and most die in early adulthood due to respiratory and cardiac failure.
Hans Schikan, Prosensa’s chief executive, said that the alliance will not only speed-up the further development of PRO051, “but will also accelerate the progress of our complementary DMD therapeutics, allowing us to reach a broader patient population”. The deal comes a month after GSK’s R&D chief Moncef Slaoui revealed that the that company was looking to expand into the orphan drugs market.
Meantime, GSK has entered into a partnership with the UK Government, the Wellcome Trust and the East of England Development Agency to develop a biotechnology science park located at the company’s site in Stevenage . Full details in tomorrow’s PharmaTimes UK News elert.
Boehringer gets OK to sell extended-release Parkinson's drug

Boehringer gets OK to sell extended-release Parkinson's drug
Boehringer noted that a further trial has shown that patients already taking Mirapexin may easily be switched overnight to the prolonged-release tablet, at the same daily dose. The new formulation causes less frequent fluctuations in the plasma concentration over 24 hours compared to the three-times daily drug, “an important aspect for physicians when choosing the best treatment option for their patient," said the company’s senior vice president of medicine, Manfred Haehl.
Boehringer quoted Mary Baker, president of the European Federation of Neurological Associations, as saying that most people with Parkinson's disease take many different pills on a daily basis, to manage their symptoms and other concomitant conditions. “Being able to reduce their pill burden without foregoing the effectiveness…can improve patient adherence to their treatment regimen," she added.
The extended-release formulation of pramipexole is currently under review with the US Food and Drug Administration.
Abbott beats forecasts as Humira sales soar again
Abbott Laboratories has posted a strong set of financials for the third quarter, helped by a one-time gain and the continuing revenue rise for Humira.
Net income leapt 36.5% to $1.48 billion, due in part to a $287 million gain from a settlement with Medtronic concerning stent technology. Group sales were up 3.5% to $7.76 billion and adjusting for the negative effect of foreign exchange, the increase would have been 8.4%.
Worldwide pharmaceutical sales slipped 1.6% to $4.06 billion, again due to currency effects, but the anti-inflammatory blockbuster Humira (adalimumab) , which is approved for indications covering rheumatoid arthritis, Crohn’s disease and psoriasis, soared once more. Sales of the drug shot up 23.8% to $1.49 billion and Abbott said that underlying demand for Humira remains strong across all three indications.
As for the company’s lipids franchise, TriCor (fenofibrate) and the recently-approved TriLipix (fenofibric acid) contributed $330 million, down 1.1%, while Niaspan (niacin) brought in $215 million, a rise of 10.6%. Of Abbott’s other products, sales of Depakote (divalproex sodium) for manic episodes, migraines and several types of epileptic disorders, were battered by generic competition and fell 70.9% to $92 million.
The prostate cancer therapy Lupron (leuprolide) fell 11.5% to $195 million, while revenues from the HIV drug Kaletra (lopinavir/ritonavi r) were down 8.7% to $353 million. Sales of the hypothyroid medication Synthroid (levothyroxine) were up 3.7% to $134 million.
Miles White, Abbott chief executive, said that the firm is performing well, having generated higher-than- expected earnings growth in the third quarter. He noted that the quarter also saw a series acquisitions, including the purchase of Solvay Pharmaceuticals. These deals “add to our diverse mix of global businesses, with new technologies, established products and emerging market infrastructure that will help us deliver sustainable industry-leading growth”, he added.
Roche sales climb on the back of Tamiflu and Avastin
Roche sales climb on the back of Tamiflu and Avastin
Roche has posted a strong set of sales figures for the third quarter this morning, with turnover rising 14% (excluding currency effects) to 12.39 billion Swiss francs, boosted by a huge rise in Tamiflu revenue.
Sales at the Swiss major’s pharmaceuticals division reached 9.93 billion francs, a rise of 15%. As usual, the oncology franchise performed well, with Avastin (bevacizumab) recording an increase of 21% to 1.59 billion francs, while MabThera/Rituxan (rituximab) grew 7% to 1.50 billion francs.
Herceptin (trastuzumab) was up 8% to 1.33 billion francs, while Tarceva (erlotinib) sales grew 11% to 319 million francs. Xeloda (capecitabine) turnover was up 11% to 326 million francs.
The most impressive performance, however, came from the influenza jab Tamiflu (oseltamivir) , sales of which leapt to 994 million francs from 101 million francs. The rise was due to the rapid worldwide spread of swine flu and Roche now expects full-year sales of Tamiflu of around 2.7 billion francs (up from a previous estimate of 2.0 billion francs) and about 700 million francs (up from 400 million francs) in 2010.
Of Roche’s other products, sales in the USA of Lucentis (ranibizumab) , for wet age-related macular degeneration, increased 21% to 296 million francs, while the hepatitis C treatment Pegasys (peginterferon alfa) was up 13% to 438 million francs. On the negative side, the transplantation product CellCept (mycophenolate mofetil) fell 26% to 362 million francs, while combined sales of Roche’s NeoRecormon and its Chugai unit’s Epogin (epoetin beta), for anaemia, declined 7% to 391 million francs.
Chief executive Severin Schwan said that sales by both pharmaceuticals and its diagnostics divisions “are significantly outgrowing their respective markets” and “based on this performance, we expect another very good full-year result”. He added that “I’m particularly pleased with the excellent progress we’re making in joining forces with Genentech”, which Roche fully acquired in March for $46.8 billion.
Roche has raised its outlook and now expects at least high single-digit sales growth for its pharmaceuticals division in 2009.
Pfizer completes acquisition
Pfizer completes acquisition
NEW YORK: Pfizer announced on Thursday it completed its acquisition of pharmaceutical rival Wyeth, a 68 billion dollar deal that cements its positions as the world's biggest drug manufacturer.
Pfizer, the maker of Viagra for erectile dysfunction and Lipitor for cholesterol, got final regulatory approval for the deal on Wednesday from US and Canadian authorities.
AstraZeneca' s Symbicort approved in Japan
AstraZeneca' s Symbicort approved in Japan
AstraZeneca has been boosted by the news that Japanese regulators have given the go-ahead to the company’s asthma drug Symbicort Turbuhaler.
Japan’s Ministry of Health, Labor and Welfare has approved Symbicort (budesonide/ formoterol) for the maintenance treatment of bronchial asthma in patients aged 16 and over when a combination therapy of an inhaled steroid and a long-acting beta-2 agonist is necessary. The approval is based on data from eight studies carried out in Japan .
Bruno Angelici, executive vice president for international sales and marketing at AstraZeneca, said that the approval will provide “a new treatment option for the approximately five million adults living with asthma in Japan ”. It will be co-promoted there by Astellas Pharma, which agreed to make an initial payment of 3.00 billion yen (about $31.5 million) for the rights in August. It may also pay up to 5.5 billion yen more, depending on sales and approval of an additional indication.
Symbicort is already a big-seller in Europe and the USA and second-quarter sales increased 24% to $551 million.
Sunday, October 18, 2009
FW: [PCM] Vacancies in Gulf,Egypt&KSA
Subject: [PCM] Vacancies in Gulf,Egypt&KSA
Date: Sat, 17 Oct 2009 11:30:48
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KSA to KSA
Riyadh Pharma ( MCPC )
Due to its major expansion is seeking for:
Medical Representatives
- Candidates should be pharmacists.
- Two years experience in similar position.
- Age should be less than 28 years.
- Transferable Iqama.
- Valid Saudi driving license.
Please send your comprehensive resume with recent photo within
One week to the following e-mail address:
nabilgh@riyadhpharm a.com
nabilgh@ riyadhpharma. com
or Fax No. +966 1 4065260
N.B. All CVs will be treated full confidentiality
From: "midseg24" <midseg24@yahoo. com>
Pharmacist vacancies in MAKKAH
Pharmacists required for working in pharmacies group in Makkah in K.S.A:
Age: between 25- 35 years old.
Good command of english is preferred.
If you are interested please send your c.v. with recent photo to:
midseg24@yahoo. com
midseg24@ yahoo.com
Egypt to KSA
For KSA
Pharmacists required
2 years experience
Dekernes Co. – Dakahlia
Candidates to be interviewed in Dekernes Co. – Portsaid St. – behind the grocery
Tel: (+2) 0198889957 – 0105619249
Al-Abeer Co. for KSA
Has vacancies for fresh graduate pharmacists
Tel: (+2) 02 37804668 – 0111746426
Al_abeerco@hotmail. com
Al_abeerco@ hotmail.com
Egypt to Egypt
Pharmacy in Dokki
Needs male/female pharmacists
Experience is NOT a must
Tel: (+2) 0101613270
Fresh graduate pharmacists needed
Pharmacy in Dokki needs
Fresh graduate male/female pharmacist
For a morning shift
Tel: (+2) 02 33382675 – 0105252278
Pharmacy in Dokki
Needs pharmacists
Tel: (+2) 02 33800184 – 33800183
Pharmacy in Al-Amireya
Needs male/female pharmacist
Night shift
Tel: (+2) 02 26234651
Pharmacy in Helmia &Qalaa
Needs male/female pharmacists
Tel: (+2) 02 23904184 - 0101416312
Pharmacy in down town
Pharmacy in down town needs
Pharmacists & assistants
Tel: (+2) 02 33374348 – 0122106731
Pharmacy in Mataria
Needs
A morning shift pharmacists
& as assistant
Tel: (+2) 02 26529255 - 0109952312
Female pharmacist required
Pharmacy in Ain-Shams
Needs female pharmacist
& second pharmacist in morning shift
Tel: (+2) 0106203223
Pharmacy in Al-Zatoon
Male/female pharmacists & assistants are needed
Tel: (+2) 0103660148 – 02 26326802
Meet Pharmacists_ coffee members on
Facebook
Big pharmacy in Misr Al-Gadida
Needs experienced pharmacists
Calling from Saturday
Tel: (+2) 02 24511125 – 24511123
Pharmacy in Bolaq Dakror
Needs assistant pharmacists
Experience is a must
Housing is available
Tel: (+2) 02 33277252 – 0108542220
Shafai pharmacies
Shafai pharmacies in Qasr Al-Ainy needs
Manager pharmacist
& a second pharmacist
Tel: (+2) 02 25325455 – 27961177 – 23647449
Pharmacy in Al-Salam
Needs manager pharmacist (in Al-Salam)
& experienced assistants (in Al-Salam & Ain Shams)
Tel: (+2) 0105001006 – 02 22807650
Pharmacists required
Pharmacists required for group of pharmacies
Tel: (+2) 02 24171088 – 24171216
Pharmacists & assistants needed
Pharmacists & assistants needed in
Hadaeq Al-Qobba – Faisal – 10 th of Ramadan
Tel: (+2) 015383933 – 0127723121 – 24536901 - 37430850
Vacany for fresh graduate pharmacists
Fresh graduate pharmacists are needed
To work in a pharmacy in Ain-Shams
All shifts
Tel: (+2) 02 26327274 - 0182218789
Assistant pharmacist required
Pharmacy in Shobra El-Khaima – Ebn Al-Hakam city
Needs assistant pharmacist
Tel: (+2) 0101700239
Pharmacy in Mataria
Pharmacy in Mataria – Kablat St.
Needs
Pharmacists
Morning & night shifts
Tel: (+2) 02 22504051 – 0163676388
Pharmacy in Abbas El-Akkad
Pharmacists needed
All shifts
Tel: (+2) 0127842433
Pharmacy in West El-Balad
Needs an experienced pharmacist
Tel: (+2) 02 25937300
Pharmacy in Ghamra
Pharmacy in Ghamra needs
Pharmacists & assistants
Morning & night shifts
Tel: (+2) 02 24863541
Pharmaceutical company
Requires:
1- District managers
2- Medical reps
All governorates
Fax: (+2) 02 37484975
Hazem505@hotmail. com
Hazem505@ hotmail.com
OMRON health care
Leading international company in health care at home
Looking for immediate hiring for the following vacancies
1- Medical reps (Cairo & Giza – only pharmacists & vets)
2- Sales reps (Cairo & Giza – university graduate)
3- Supervisor (Cairo & Giza – previous experience is a must)
info@health- xc.com
info@ health-xc.com
Fax: (+2) 02 22631483
Smart royal for pharmaceuticals
Requires
1- Medical reps
2- Seniors
3- Field force supervisor
Cairo & Giza
Send your CV to:
Smart_royal@ hotmail.com
Smart_royal@ hotmail.com
Fax: (+2) 02 26703988
Egapico pharma company
Requires
1- Supervisors
2- Medical reps
All governorates
Full/part time
Fax: (+2) 050 2236212 - 0127491515
From: Mahmoud Azmy <mood_azmy@yahoo. com>
A multinational company
is seeking for medical representatives in Damietta, Port Said and Ismailia The candidates should be : 1) Pharmacist, Veterinarian, Physician. 2) Have 1 year experience is preferred. Please send your CV to: mood_azmy@yahoo. com
mood_azmy@ yahoo.com
Egypt to Gulf
Nestle
The world leading food & Nutrition Company
Requires candidates for its operation in the Gulf
Medical representative
Candidate profile:
· Holding a degree in pharmaceutical science
· with 2-3 years of experience in the same role
· have excellent communication skills in both English & Arabic
Candidates meeting the above requirements should register their CVs
online & apply to the relevant position posted on the website
http://www.nestle- family.com/ careers/english/
Applications will be treated in strict confidence
Only short listed candidates will be contacted
RAK medical & health Sciences University
Ras Al Khaimah, U.A.E.
Invites application for:
Assistance professor – Biochemistry / Pharmacology
Detailed specifications for each position are available on the
University site www.rakmhsu. com
Suitable candidates are invited to download the application form from the university website & send within 10 days of this notification to:
The officer of HR
RAK medical & health Sciences University
P.O. Box: 11172
Ras Al Khaimah, U.A.E.
E-mail: hrd@rakmhsu. ae
hrd@ rakmhsu.ae
mohdriaz@eim. ae
mohdriaz@ eim.ae
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